We have all the tools we need for the elimination of cervical cancer, a largely preventable cancer that annually kills more than 300,000 women worldwide—the vast majority in low- and middle-income countries.
These are just a few of the simple efforts underway to reach more women with prevention and treatment—and ultimately eliminate cervical cancer. It’s challenging, of course, to expand access to, and integrate a new cancer screening technology into health systems burdened by…
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Keri Topperwien with her son Chace who died in 2012 from leukaemia. She hopes her research will help increase the number of Māori bone marrow donations. Photo / Supplied
A mum who set up a charity to support whanāu who have a child with cancer has been awarded a community research grant from the Health Research Council (HRC) to explore Māori perspectives on bone marrow donation.
Keri Topperwien (Ngāti Awa, Ngāti Porou) and her husband established the Dream Chaser Foundation following the death of their son.
Chace (Ngāti Awa, Ngāti Porou, Tūhoe) was 3 when he died in 2012 after being diagnosed with acute myeloid leukaemia, an aggressive type of cancer of the blood and bone marrow.
Topperwien will use the HRC Ngā Kanohi Kitea development grant to build connections and prepare to undertake kaupapa Māori research that targets opportunities for increasing the number of bone marrow donors in Aotearoa, particularly among Māori.
“The best chance Chace had of surviving leukaemia was a bone marrow transplant to replace the cancerous cells within his bones with donated healthy marrow,” Topperwien says.
“However, unlike with blood, certain markers need to align to be a bone marrow match, meaning that Chace’s match was most likely going to be from a Māori donor. At the time, there were 26 million bone marrow donors on the international bone marrow registry, however only 6000 were Māori – but none was a match to our son.”
Topperwien…
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SAVANNAH, Ga., Oct. 07, 2022 (GLOBE NEWSWIRE) — P23 Labs, a molecular laboratory specializing in preventative diagnostic testing, acknowledges World Mental Health Day with an awareness weekend on Oct. 8-9, aimed to foster early mental disorder detection and its efficient treatment. Both practitioners and individuals are encouraged to leverage the power of personalized medicine in mental health treatment, and the P23 team provides its input.
P23 contributes in the best viable way it can — by harnessing the Pharmacogenomics (PGx) perspective to the issue. Pharmacogenomics is the study of how people respond differently to drug therapy based on their genetic makeup or genes.
P23 Optimum PGx is a representative of DNA testing for medication optimization. It allows healthcare providers to choose the right drug and dose that are likely to work best for each individual patient. Tailoring a patient’s medication to their unique genetic characteristics may one day replace the one-size-fits-all approach to drug selection and dosing that is commonly used today.
The goal of Mental Health Awareness Weekend is to create a supportive environment by connecting doctors, pharmacists, and individuals with appropriate resources and information, as well as to bring attention to mental health treatment within the principles of precision medicine.
P23’s Mental…
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Genes can play a big role in both your overall health and your risk of inheriting certain diseases. As the scientific community has learned more about the role of genetics in diseases over the past two decades, knowing your family medical history is becoming increasingly important. Case in point— a heart condition called hypertrophic cardiomyopathy (more frequently referred to as HCM). HCM is estimated to affect approximately between 1 in every 500 people and 1 in 200 people and is also the most common genetic heart condition—despite this, many people with the disease don’t even know they have it.*[1],[2],[3]
What is HCM?
In someone with HCM, the walls of the heart become thicker than they should be, making it difficult for the heart to efficiently pump oxygenated blood throughout the body.[4] This means that a heart affected by HCM has to work harder, so those with HCM can experience a lack of energy, a rapid heartbeat, chest pain, shortness of breath or other symptoms, especially in the context of physical activity.[5]
Recognizing the symptoms of HCM is important in getting an early and accurate diagnosis. Historically, HCM has been hard to diagnose since patients can have mild, nonspecific symptoms, symptoms that mimic other conditions, and in some case, no symptoms at all.[6] Possible symptoms that signal HCM can include shortness of breath, dizziness, fainting, or heart palpitations. These are also common symptoms of asthma, high blood pressure, and more. Only a…
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HARTFORD, CT – 03.12.2019 – HEALTH SCREENING – “I could probably lose a little weight,” says Luz Alicea, 57, of Hartford, at right, after getting her blood pressure taken by heath tech Trudy Powell-McGee, of Stratford, at a free health screening in an eighteen-foot mobile unit outside of Community Health Services on Albany Ave. in Hartford on Tuesday. About fifty residents had their cholesterol levels, blood pressure and body mass index (BMI) checked. They received the screening results immediately. Credit: Patrick Raycraft | Hartford Courant
Marcus Wright was 27 years old, the healthiest he had ever been while training for a marathon, when he had a heart attack.
Genetic testing revealed Wright has a unique condition, resulting from a genetic mutation that causes coronary artery disease, which is now helping researchers at Ohio State develop a new way of treating high cholesterol through new medications.
According to the Centers for Disease Control and Prevention, coronary artery disease is caused by deposits of cholesterol and other substances building up in the arteries supplying blood to the heart, which may partially or totally stop blood flow.
Wright said he came to the Wexner Medical Center at Ohio State and was seen by Dr. Ernest Mazzaferri Jr., an interventional cardiologist.
Sara Koenig, an assistant professor of physiology and cell biology at Ohio State, said typically after a heart attack, doctors will clean out the arteries if they are…
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Vacation can take people to all kinds of new and interesting places.
Some people have a goal of visiting all 50 states and try to visit a new one each year or two. Some people have a bucket list of baseball stadiums they want to see or national parks they want to visit. I even know someone who loves to visit historic libraries that were built by Andrew Carnegie, and he goes to see them all across the country.
Some people are “genealogy tourists,” and they visit locations where they can conduct family research. They may visit cemeteries of their ancestors and make rubbings of headstones. They may drive hundreds of miles to scroll through microfilm at a small-town newspaper. They may also visit a library to pore over city directories, yearbooks and other archives.
The Norfolk Public Library often welcomes these traveling family researchers. Genealogists from as far away as Washington and Arizona have looked through the library’s materials, scouring for birth announcements, addresses and obituaries to complete their family trees.
Several years ago, the library worked with the Norfolk Daily News to get all the newspaper’s archives into a digital format that was easily searchable. The new digital archive was available in the library and greatly reduced searching time. Instead of scrolling through rolls of microfilm, the researcher simply had to type…
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But while a monkeypox test exists, it requires lab workers to do each step by hand, Morice says. Federal guidelines say testing should be done only by swabbing the lesions of a person suspected to have the virus. These lesions look like pimples or blisters and can appear on the face, hands, feet, around the genitals or anus, or inside the mouth or rectum. Then the swabbed samples undergo a PCR—or polymerase chain reaction—test, which involves extracting genetic material and amplifying it to look for the presence of monkeypox virus’s DNA.
That makes testing slow going. Commercial labs like the Mayo Clinic have been working to automate the process for extracting and amplifying viral DNA. Until recently, the clinic was able to process only 20 to 30 tests using the manual protocol, but soon it will be able to run several hundred tests a day, says Morice.
This kind of test raises some other issues too. “The current tests force you to swab a lesion. For people with internal lesions, that might not be possible, or it’s very painful,” Makofane says.
Another issue is it can’t be used until a person has visible symptoms—and it can take several days for a rash to appear. Some people may have very subtle, or very few, lesions. While it’s not clear if the disease can spread before the blisters form, Rivers says it would be better to catch an infection earlier on, so that people can access treatment and vaccines as soon as possible. For the best chance of preventing the onset of the disease, the CDC says, the vaccine should be given within four days from the date of exposure.
Like Covid-19 testing in the early days of the pandemic, monkeypox tests must be ordered by a physician. Morice says many doctors might not know to test for monkeypox because it’s such a new disease in the US, or they may not consider referring patients who are not in what they think of as at-risk populations. While most cases have been in men who have sex with men, not all are. For example, health officials in Indiana have reported that around 20 percent of the state’s cases have been in women, and two infections have been identified in children.
Financial constraints, stigmatization, and lack of insurance or transportation to testing sites can also be barriers that keep some people with symptoms from seeking testing.
The US Food and Drug Administration says monkeypox should be diagnosed only by swabbing lesions, but a study published in June by researchers in Spain points to…
COLUMBUS, Ohio (AP) — A man accused of raping and impregnating a 9-year-old Ohio girl who traveled to Indiana for an abortion was ordered held without bond Thursday by a judge who cited overwhelming evidence and the fact that he apparently is living in the U.S. illegally.
Gerson Fuentes, 27, faces two counts of raping the girl, who turned 10 before having the abortion in a case that has become a flashpoint in the national discussion about access to the procedure since the Supreme Court overturned Roe v. Wade. He has pleaded not guilty.
If convicted, Fuentes, who is from Guatemala, faces the possibility of life in prison with no chance of parole. That penalty and “not having any ties to this community that can be proved legally makes it a substantial flight risk,” Franklin County Judge Julie Lynch said after a 35-minute hearing.
The girl confirmed that Fuentes attacked her, Fuentes confessed to Columbus police detectives, and DNA testing of the aborted fetus confirmed Fuentes was the father, Franklin County Prosecutor Dan Meyer and Detective Jeffrey Huhn said in court Thursday.
Huhn said he was unable, when searching multiple databases, to find any evidence that Fuentes was in the country legally.
In denying bond, Lynch cited that evidence, the violence of the crime and the fact that Fuentes had been living in the same home with the girl and her mother.
“To allow him to return to that home, the traumatic and psychological impact would be undeserving to an alleged victim,” Lynch said. She also cited the “physical, and mental and emotional trauma” the girl suffered from enduring the rapes and the abortion, and finding her case at the center of the country’s abortion debate.
The case gained national attention after an Indianapolis physician, Dr. Caitlin Bernard, said the child had to travel to Indiana due to Ohio banning abortions at the first detectable “fetal heartbeat” after the U.S. Supreme Court overturned the landmark Roe v. Wade ruling.
Fuentes’ attorney, Bryan Bowen, argued against a no-bond hearing and unsuccessfully asked Lynch to set a reasonable bond. He said there was no evidence of physical abuse outside of the rapes or that the girl had been put under the influence of drugs or alcohol. He also said that Fuentes had family ties in Columbus, that he had a job, and that there was no evidence of a criminal history. Fuentes has lived in the area about seven years.
“We’ve heard evidence about the nature of the offense, but we have…
A blood test that can help prevent stroke victims from having another attack is now being offered on the NHS in a move that experts say will save lives.
The test picks up genetic clues that show if patients will not respond to standard treatment – allowing doctors to switch them on to more effective drugs.
Experts say that roughly 25,000 Britons fall into this category, and until now it has been impossible to identify them.
It comes three months after The Mail on Sunday published details of a major report calling for widespread use of the genetic tests, which experts say could prevent tens of thousands of strokes and heart attacks every year.
A blood test that can help prevent stroke victims from having another attack is now being offered on the NHS in a move that experts say will save lives. (File image)
Dr Alex Doney, a stroke specialist at Ninewells Hospital in Dundee, the first UK NHS unit to offer the test, says: ‘Genetic testing for stroke patients will save lives.
‘For years, we’ve treated stroke patients on a one-size-fits-all basis, meaning people with completely different genetic make-ups receive exactly the same dose of the same drug. Yet we know that for many patients, the current drugs work no better than taking a placebo.’
While the test is being used across 33 NHS hospitals in Scotland, the UK health watchdog, the National Institute for Health and Care Excellence (NICE), is reviewing it for more widespread use.
There are some 1.3 million stroke survivors in the UK. The attacks – the most common cause of disability – happen when there are problems with the blood supply to the brain.
There are two types. The most common is ischaemic stroke, where the blood supply is stopped due to a blood clot. These account for about nine in ten strokes.
It comes three months after The Mail on Sunday published details of a major report calling for widespread use of the genetic tests, which experts say could prevent tens of thousands of strokes and heart attacks every year. (Picture posed by model)
The other is a haemorrhagic stroke, which happens when there is a bleed on the brain because a weakened blood vessel that supplies the organ has ruptured.
This can happen for a number of reasons, including injury to the head, abnormalities in the blood vessels and bleeding disorders.
Most sufferers must take daily blood-thinning medication to prevent another stroke. The most common, for ischaemic strokes, is clopidogrel, which stops small blood cells…
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SPECIAL NOTE
SPORTS REGISTRATION: Danville Parks and Recreation’s registration period for youth football and cheerleading is now open until Aug. 5. This season’s offerings are available for children ages 5-12. Flag football is for children ages 5-6, and tackle football is for children ages 7-12. Registration for football is $35, and registration for cheerleading is $40. Additional fees may apply. Sports officials are also needed. Those with relevant experience are encouraged to contact 434-799-5214. Those interested in registering for football and cheerleading may do so by calling 434-799-5214 or by signing up online at playdanvilleva.com.
TODAY, JULY 12
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SENIORS ON THE MOVE: The senior citizen’s program at the Cherrystone Missionary Baptist Association, 5551 Tom Fork Road, Ringgold, meets every Tuesday from 11 a.m. to 1 p.m. to play bingo and dominos. Also, there’s a computer awareness class from 10 to 11 a.m. and 1 to 2 p.m., senior exercise from noon to 12:20 p.m. with lunch served from 12:20 to 1 p.m. All seniors 60 years and older are welcome. For additional information, call Frances Garlin at 434-822-6453, Barbara Williams at 434-713-5271, and for computer awareness and exercise, Kathy B. Ramsey at 434-251-0379.
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