HoloGRAFT in comparison with other cell-free DNA analysis methods

Omixon to commercialize a cell-free DNA assay for transplant monitoring developed and validated by a transplant physician

BUDAPEST, HUNGARY, June 4, 2022 /EINPresswire.com/ — Omixon Biocomputing, Kft announced today that it has completed a collaborative agreement with Organ Monitoring Group to develop post-transplant monitoring product HoloGRAFT. As part of the agreement Omixon secured an exclusive option to acquire all remaining shares of Organ Monitoring Group BV (OMG) after having acquired 50% of OMG. Organ Monitoring Group BV owns some exclusive license rights to commercialize patented methods using copy-number-variant markers using digital polymerase chain reaction (dPCR) technology for transplant monitoring. The method was developed and validated by John Whitlam, MD, PhD, Clinical Lead, Kidney Transplantation at Austin Health, and colleagues at the Murdoch Children’s Research Institute in Melbourne, Australia. Omixon will fund collaborative development programs related to transplant monitoring applications while Mr Doug Bost, Founder and CEO of OMG, joins Omixon as Member, Board of Directors, and Vice-President of Transplant Monitoring Products. Financial details of the transaction were not disclosed.

“Transplant recipients need to take immunosuppressive drugs for the rest of their lives. Too much of immunosuppression leads to cancer or infections, too little leads to rejection. However, each individual patient has patient-specific responses to the transplant. Frequent monitoring of transplant rejection can help to recognise rejection early when it can be treated without irreversible damage to the organ. Currently…