Family: Ephraim A Otis, III / Rebecca Underhill (F1322)
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 | Ephraim Otis, Jr (1734-1816)
|
 | Sarah Harris (1750-1827) |
| Ephraim A Otis, III (1772-1850)
|
| Rebecca Underhill ( -1847) |
| Isaac Otis (1798-1853)  |