Nathan married Sarah Powell on 2 Nov 1818 in Clarke, Georgia, USA. Sarah (daughter of Henry Powell and Mary Elizabeth "Polly", "Sary" Pope) was born on 18 Mar 1800 in Clarke, Georgia, United States; died on 27 Oct 1850 in Butler, Alabama, United States; was buried in Georgiana, Butler County, Alabama, United States of America. [Group Sheet] [Family Chart]

1. James Agee Bransford was born on 22 September 1820 in Alabama, United States of America; died on 24 July 1872 in Farmerville, Union Parish, Louisiana, United States of America; was buried in Farmerville, Union Parish, Louisiana, United States of America.
2. John Henry Bransford was born on 19 January 1828; died on 1 September 1903 in Cass County, Texas, United States of America; was buried in Atlanta, Cass County, Texas, United States of America.
3. Nathan Upson Bransford was born in Jun 1834 in Butler Co, Alabama, USA; died in Bet. 1910–1920 in Gillespie County, Texas, USA; was buried in Gillespie County, Texas, United States of America.
4. Mary Bransford